Is science our only route to knowledge? Are there questions science cannot answer? Might science provide us with grounds for supposing there is a God, or that there is not? Join three leading, provocative and controversial thinkers as they discuss these and other fascinating questions concerning the limits of our understanding.

Dr Rupert Sheldrake is a biologist and author of more than 80 scientific papers and 10 books, including The Science Delusion. He was a fellow of Clare College, Cambridge University, and a research fellow of the Royal Society.

Dr James Le Fanu is a general practitioner in South London and writes a regular column on medicine and science for The Daily Telegraph and on natural history for The Oldie. His books include The Rise and Fall of Modern Medicine, winner of The Los Angeles Times book prize in 2001, and Why Us: How Science Rediscovered the Mystery of Ourselves.

Martin Robbins is a researcher and writer who appears regularly in The Guardian, New Statesman and VICE Magazine. His writing explores themes of denial, conflict and mystery at the fringes of science and human understanding, where evidence and culture collide.

Presented by Centre for Inquiry